Evergreen veteran Shaun Marsh will skipper the side in the absence of brother Mitch when he takes to the field to begin his 20th domestic season with WA.
There will be a WA debutant come the morning, with uncapped pair Cameron Gannon and Lance Morris both named in the 12-player squad.
Cameron Green will play as a batsman only as he continues to fine-tune a revised bowling action.
South Australia v Western Australia
Saturday 10 – Tuesday 13 October
Karen Rolton Oval, Adelaide
Western Australia Squad:
Shaun Marsh (C)
12th man will be named at the toss.